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Epigenetic Silencing of TFPI-2 in Canine Diffuse Large B-Cell Lymphoma

Epigenetic modifications are important early events during carcinogenesis. In particular, hypermethylation of CpG islands in the promoter region of tumor suppressor genes is a well-known mechanism of gene silencing that contributes to cancer development and progression. Tissue factor pathway inhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ferraresso, Serena, Bresolin, Silvia, Aricò, Arianna, Comazzi, Stefano, Gelain, Maria Elena, Riondato, Fulvio, Bargelloni, Luca, Marconato, Laura, te Kronnie, Geertruy, Aresu, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973630/
https://ncbi.nlm.nih.gov/pubmed/24695110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092707
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