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The Toll-Like Receptor 4 Polymorphism Asp299Gly but Not Thr399Ile Influences TLR4 Signaling and Function
The common, co-segregating Toll-like receptor 4 (TLR4) non-synonymous single nucleotide polymorphisms (SNPs), Asp299Gly and Thr399Ile, are associated with hyporesponsiveness to inhaled lipopolysaccharide (LPS) and increased susceptibility to Gram negative pathogens in humans. The purpose of this stu...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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Public Library of Science
2014
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973565/ https://ncbi.nlm.nih.gov/pubmed/24695807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093550 |
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