Apelin Increases Cardiac Contractility via Protein Kinase Cε- and Extracellular Signal-Regulated Kinase-Dependent Mechanisms

BACKGROUND: Apelin, the endogenous ligand for the G protein-coupled apelin receptor, is an important regulator of the cardiovascular homoeostasis. We previously demonstrated that apelin is one of the most potent endogenous stimulators of cardiac contractility; however, its underlying signaling mecha...

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Detalhes bibliográficos
Main Authors: Perjés, Ábel, Skoumal, Réka, Tenhunen, Olli, Kónyi, Attila, Simon, Mihály, Horváth, Iván G., Kerkelä, Risto, Ruskoaho, Heikki, Szokodi, István
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973555/
https://ncbi.nlm.nih.gov/pubmed/24695532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093473
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