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EGFR Signaling Promotes β-Cell Proliferation and Survivin Expression during Pregnancy

Placental lactogen (PL) induced serotonergic signaling is essential for gestational β-cell mass expansion. We have previously shown that intact Epidermal growth factor –receptor (EGFR) function is a crucial component of this pathway. We now explored more specifically the link between EGFR and pregna...

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Bibliografiske detaljer
Main Authors: Hakonen, Elina, Ustinov, Jarkko, Palgi, Jaan, Miettinen, Päivi J., Otonkoski, Timo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973552/
https://ncbi.nlm.nih.gov/pubmed/24695557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093651
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