The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling

The recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV), a betacoronavirus, is associated with severe pneumonia and renal failure. The environmental origin of MERS-CoV is as yet unknown; however, its genome sequence is closely related to those of two bat coronaviruses, named BtC...

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Bibliografiska uppgifter
Huvudupphovsmän: Matthews, Krystal L., Coleman, Christopher M., van der Meer, Yvonne, Snijder, Eric J., Frieman, Matthew B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for General Microbiology 2014
Ämnen:
Animal
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973478/
https://ncbi.nlm.nih.gov/pubmed/24443473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.062059-0
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