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Forebrain melanocortin signaling enhances the hindbrain satiety response to CCK-8

Melanocortin 4 receptors (MC4R) are hypothesized to mediate the central nervous system actions of leptin to enhance the satiety effects of cholecystokinin (CCK). To further elucidate this mechanism, we confirmed that peripheral administration of CCK-8 is less effective in producing this effect in MC...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blevins, James E., Morton, Gregory J., Williams, Diana L., Caldwell, David W., Bastian, Lloyd S., Wisse, Brent E., Schwartz, Michael W., Baskin, Denis G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973398/
https://ncbi.nlm.nih.gov/pubmed/19109369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90544.2008
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