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Mx Proteins: Antiviral Gatekeepers That Restrain the Uninvited

SUMMARY: Fifty years after the discovery of the mouse Mx1 gene, researchers are still trying to understand the molecular details of the antiviral mechanisms mediated by Mx proteins. Mx proteins are evolutionarily conserved dynamin-like large GTPases, and GTPase activity is required for their antivir...

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Autors principals: Verhelst, Judith, Hulpiau, Paco, Saelens, Xavier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973384/
https://ncbi.nlm.nih.gov/pubmed/24296571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00024-13
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