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Mx Proteins: Antiviral Gatekeepers That Restrain the Uninvited

SUMMARY: Fifty years after the discovery of the mouse Mx1 gene, researchers are still trying to understand the molecular details of the antiviral mechanisms mediated by Mx proteins. Mx proteins are evolutionarily conserved dynamin-like large GTPases, and GTPase activity is required for their antivir...

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Autori principali: Verhelst, Judith, Hulpiau, Paco, Saelens, Xavier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973384/
https://ncbi.nlm.nih.gov/pubmed/24296571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00024-13
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