Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.

The heavy chains of both botulinum neurotoxin type B and tetanus toxin form channels in planar bilayer membranes. These channels have pH-dependent and voltage-dependent properties that are remarkably similar to those previously described for diphtheria toxin. Selectivity experiments with anions and...

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Bibliographic Details
Main Authors: Hoch, D H, Romero-Mira, M, Ehrlich, B E, Finkelstein, A, DasGupta, B R, Simpson, L L
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC397338/
https://ncbi.nlm.nih.gov/pubmed/3856850
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