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Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.

The heavy chains of both botulinum neurotoxin type B and tetanus toxin form channels in planar bilayer membranes. These channels have pH-dependent and voltage-dependent properties that are remarkably similar to those previously described for diphtheria toxin. Selectivity experiments with anions and...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Hoch, D H, Romero-Mira, M, Ehrlich, B E, Finkelstein, A, DasGupta, B R, Simpson, L L
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1985
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397338/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856850/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.6.1692
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