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RecA-dependent programmable endonuclease Ref cleaves DNA in two distinct steps
The bacteriophage P1 recombination enhancement function (Ref) protein is a RecA-dependent programmable endonuclease. Ref targets displacement loops formed when an oligonucleotide is bound by a RecA filament and invades homologous double-stranded DNA sequences. Mechanistic details of this reaction ha...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973344/ https://ncbi.nlm.nih.gov/pubmed/24371286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1342 |
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