Length-dependent processing of telomeres in the absence of telomerase

In the absence of telomerase, telomeres progressively shorten with every round of DNA replication, leading to replicative senescence. In telomerase-deficient Saccharomyces cerevisiae, the shortest telomere triggers the onset of senescence by activating the DNA damage checkpoint and recruiting homolo...

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Detaylı Bibliyografya
Asıl Yazarlar: Fallet, Emilie, Jolivet, Pascale, Soudet, Julien, Lisby, Michael, Gilson, Eric, Teixeira, Maria Teresa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973311/
https://ncbi.nlm.nih.gov/pubmed/24393774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1328
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