Binary recombinase systems for high-resolution conditional mutagenesis

Conditional mutagenesis using Cre recombinase expressed from tissue specific promoters facilitates analyses of gene function and cell lineage tracing. Here, we describe two novel dual-promoter-driven conditional mutagenesis systems designed for greater accuracy and optimal efficiency of recombinatio...

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Detalhes bibliográficos
Main Authors: Hermann, Mario, Stillhard, Patrick, Wildner, Hendrik, Seruggia, Davide, Kapp, Viktor, Sánchez-Iranzo, Héctor, Mercader, Nadia, Montoliu, Lluís, Zeilhofer, Hanns Ulrich, Pelczar, Pawel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973285/
https://ncbi.nlm.nih.gov/pubmed/24413561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1361
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