Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B

The chromosomal passenger complex (CPC) plays a pivotal role in controlling accurate chromosome segregation and cytokinesis during cell division. Aurora-B, one of the chromosomal passenger proteins, is important for the mitotic spindle assembly checkpoint (SAC). Previous reports noted that Aurora-C...

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Autores principales: Lin, B-W, Wang, Y-C, Chang-Liao, P-Y, Lin, Y-J, Yang, S-T, Tsou, J-H, Chang, K-C, Liu, Y-W, Tseng, J T, Lee, C-T, Lee, J-C, Hung, L-Y
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973241/
https://ncbi.nlm.nih.gov/pubmed/24603334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.37
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