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D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation

Non-enzymatic glycation of proteins by reducing saccharides for instance D-glucose is an important post-translational modification regulating protein function. Already two centuries ago, D-glucose (Glc) was identified in the urine of diabetic patients. Recently, abnormally high level of D-ribose (Ri...

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Bibliografiske detaljer
Main Authors: Han, C, Lu, Y, Wei, Y, Wu, B, Liu, Y, He, R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973213/
https://ncbi.nlm.nih.gov/pubmed/24625976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.89
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