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Harnessing FOXP3(+) regulatory T cells for transplantation tolerance

Early demonstrations that mice could be tolerized to transplanted tissues with short courses of immunosuppressive therapy and that with regard to tolerance to self, CD4(+)FOXP3(+) regulatory T cells (Tregs) appeared to play a critical role, have catalyzed strategies to harness FOXP3-dependent proces...

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Autori principali: Waldmann, Herman, Hilbrands, Robert, Howie, Duncan, Cobbold, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973097/
https://ncbi.nlm.nih.gov/pubmed/24691478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67226
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