DLC1-dependent parathyroid hormone–like hormone inhibition suppresses breast cancer bone metastasis

Bone metastasis is a frequent complication of breast cancer that is often accelerated by TGF-β signaling; however, little is known about how the TGF-β pathway is regulated during bone metastasis. Here we report that deleted in liver cancer 1 (DLC1) is an important regulator of TGF-β responses and os...

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Hauptverfasser: Wang, Yufeng, Lei, Rong, Zhuang, Xueqian, Zhang, Ning, Pan, Hong, Li, Gang, Hu, Jing, Pan, Xiaoqi, Tao, Qian, Fu, Da, Xiao, Jianru, Chin, Y. Eugene, Kang, Yibin, Yang, Qifeng, Hu, Guohong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973085/
https://ncbi.nlm.nih.gov/pubmed/24590291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71812
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