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Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch
In sensory neurons, mechanotransduction is sensitive, fast and requires mechanosensitive ion channels. Here we develop a new method to directly monitor mechanotransduction at defined regions of the cell-substrate interface. We show that molecular-scale (~13 nm) displacements are sufficient to gate m...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Pub. Group
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973071/ https://ncbi.nlm.nih.gov/pubmed/24662763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4520 |
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