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A stomatin dimer modulates the activity of acid-sensing ion channels

Stomatin proteins oligomerize at membranes and have been implicated in ion channel regulation and membrane trafficking. To obtain mechanistic insights into their function, we determined three crystal structures of the conserved stomatin domain of mouse stomatin that assembles into a banana-shaped di...

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Bibliografiske detaljer
Main Authors: Brand, Janko, Smith, Ewan St J, Schwefel, David, Lapatsina, Liudmila, Poole, Kate, Omerbašić, Damir, Kozlenkov, Alexey, Behlke, Joachim, Lewin, Gary R, Daumke, Oliver
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433786/
https://ncbi.nlm.nih.gov/pubmed/22850675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.203
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