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Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion.

Mouse mammary epithelial cells (MMEC) secrete certain milk proteins only when cultured on floating collagen gels. We demonstrate here that modulation of milk proteins by substrata is manifested at several regulatory levels; (i) Cells cultured on floating collagen gels have 3- to 10-fold more casein...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lee, E Y, Lee, W H, Kaetzel, C S, Parry, G, Bissell, M J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856271/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.5.1419
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