Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion.

Mouse mammary epithelial cells (MMEC) secrete certain milk proteins only when cultured on floating collagen gels. We demonstrate here that modulation of milk proteins by substrata is manifested at several regulatory levels; (i) Cells cultured on floating collagen gels have 3- to 10-fold more casein...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lee, E Y, Lee, W H, Kaetzel, C S, Parry, G, Bissell, M J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1985
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856271/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.5.1419
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