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Acidic pH requirement for insertion of colicin E1 into artificial membrane vesicles: relevance to the mechanism of action of colicins and certain toxins.

The channel-forming activity of colicin E1 in artificial membranes is known to increase at low pH values and to have a maximum near pH 4 in such membrane vesicles. The present work demonstrates that this pH dependence of activity can be attributed to membrane binding. Maximal binding of colicin E1 a...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Davidson, V L, Brunden, K R, Cramer, W A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1985
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397266/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2579396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.5.1386
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