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Computational studies of colicin insertion into membranes: The closed state

Colicins are water-soluble toxins that, upon interaction with membranes, undergo a conformational change, insert, and form pores in them. Pore formation activity is localized in a bundle of 10 α-helices named the pore-forming domain (PFD). There is evidence that colicins attach to the membrane via a...

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Autori principali: Prieto, Lidia, Lazaridis, Themis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995820/
https://ncbi.nlm.nih.gov/pubmed/20941706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22866
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