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Cyclization of RNA 3'-terminal phosphate by cyclase from HeLa cells proceeds via formation of N(3')pp(5')A activated intermediate.

RNA 3'-terminal phosphate cyclase has been partially purified from HeLa cells. In the presence of ATP and Mg2+, cyclase preparations catalyze conversion of RNA 3'-terminal phosphate to the 2',3'-cyclic phosphodiester. The mechanism of 3'-phosphate cyclization was studied wit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Filipowicz, W, Strugala, K, Konarska, M, Shatkin, A J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1985
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC397251/
https://ncbi.nlm.nih.gov/pubmed/2579395
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