लोड हो रहा है...
ALK5 inhibition blocks TGFβ-induced CCN1 expression in human foreskin fibroblasts
The potent profibrotic cytokine TGFβ induces connective tissue growth factor (CCN2/CTGF) is induced in fibroblasts in a fashion sensitive to SB-431542, a specific pharmacological inhibitor of TGFβ type I receptor (ALK5). In several cell types, TGFβ induces CCN1 but suppresses CCN3, which opposes CCN...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Springer Netherlands
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972393/ https://ncbi.nlm.nih.gov/pubmed/24567145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-014-0229-7 |
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