Systemic Administration of Propentofylline, Ibudilast, and (+)-Naltrexone Each Reverses Mechanical Allodynia in a Novel Rat Model of Central Neuropathic Pain

Central neuropathic pain (CNP) is a debilitating consequence of central nervous system (CNS) damage for which current treatments are ineffective. To explore mechanisms underlying CNP, we developed a rat model involving T13/L1 dorsal root avulsion. The resultant dorsal horn damage creates bilateral b...

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Bibliografiska uppgifter
Huvudupphovsmän: Ellis, Amanda, Wieseler, Julie, Favret, Jacob, Johnson, Kirk W., Rice, Kenner C., Maier, Steven F., Falci, Scott, Watkins, Linda R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972272/
https://ncbi.nlm.nih.gov/pubmed/24412802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.12.007
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