Caspase-2 Maintains Bone Homeostasis by Inducing Apoptosis of Oxidatively-Damaged Osteoclasts

Osteoporosis is a silent disease, characterized by a porous bone micro-structure that enhances risk for fractures and associated disabilities. Senile, or age-related osteoporosis (SO), affects both men and women, resulting in increased morbidity and mortality. However, cellular and molecular mechani...

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Bibliographische Detailangaben
Hauptverfasser: Sharma, Ramaswamy, Callaway, Danielle, Vanegas, Difernando, Bendele, Michelle, Lopez-Cruzan, Marisa, Horn, Diane, Guda, Teja, Fajardo, Roberto, Abboud-Werner, Sherry, Herman, Brian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972236/
https://ncbi.nlm.nih.gov/pubmed/24691516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093696
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