Discovery of a Natural Product-Like iNOS Inhibitor by Molecular Docking with Potential Neuroprotective Effects In Vivo

In this study, we applied structure-based virtual screening techniques to identify natural product or natural product-like inhibitors of iNOS. The iNOS inhibitory activity of the hit compounds was characterized using cellular assays and an in vivo zebrafish larvae model. The natural product-like com...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Zhong, Hai-Jing, Liu, Li-Juan, Chong, Cheong-Meng, Lu, Lihua, Wang, Modi, Chan, Daniel Shiu-Hin, Chan, Philip Wai Hong, Lee, Simon Ming-Yuen, Ma, Dik-Lung, Leung, Chung-Hang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972188/
https://ncbi.nlm.nih.gov/pubmed/24690920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092905
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi