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Three-Step Method for Proliferation and Differentiation of Human Embryonic Stem Cell (hESC)-Derived Male Germ Cells

The low efficiency of differentiation into male germ cell (GC)-like cells and haploid germ cells from human embryonic stem cells (hESCs) reflects the culture method employed in the two-dimensional (2D)-microenvironment. In this study, we applied a three-step media and calcium alginate-based 3D-cultu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lim, Jung Jin, Shim, Myung Sun, Lee, Jeoung Eun, Lee, Dong Ryul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972183/
https://ncbi.nlm.nih.gov/pubmed/24690677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090454
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