A Teratocarcinoma-Like Human Embryonic Stem Cell (hESC) Line and Four hESC Lines Reveal Potentially Oncogenic Genomic Changes

The first Swiss human embryonic stem cell (hESC) line, CH-ES1, has shown features of a malignant cell line. It originated from the only single blastomere that survived cryopreservation of an embryo, and it more closely resembles teratocarcinoma lines than other hESC lines with respect to its abnorma...

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Hauptverfasser: Hovatta, Outi, Jaconi, Marisa, Töhönen, Virpi, Béna, Frédérique, Gimelli, Stefania, Bosman, Alexis, Holm, Frida, Wyder, Stefan, Zdobnov, Evgeny M., Irion, Olivier, Andrews, Peter W., Antonarakis, Stylianos E., Zucchelli, Marco, Kere, Juha, Feki, Anis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859053/
https://ncbi.nlm.nih.gov/pubmed/20428235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010263
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