Lack of Matrilin-2 Favors Liver Tumor Development via Erk1/2 and GSK-3β Pathways In Vivo

Matrilin-2 (Matn2) is a multidomain adaptor protein which plays a role in the assembly of extracellular matrix (ECM). It is produced by oval cells during stem cell-driven liver regeneration. In our study, the impact of Matn2 on hepatocarcinogenesis was investigated in Matn2(-/-) mice comparing them...

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Detalhes bibliográficos
Main Authors: Fullár, Alexandra, Baghy, Kornélia, Deák, Ferenc, Péterfia, Bálint, Zsák, Yvonne, Tátrai, Péter, Schaff, Zsuzsa, Dudás, József, Kiss, Ibolya, Kovalszky, Ilona
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972106/
https://ncbi.nlm.nih.gov/pubmed/24691449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093469
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