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A Structure-Based Model for Predicting Serum Albumin Binding

One of the many factors involved in determining the distribution and metabolism of a compound is the strength of its binding to human serum albumin. While experimental and QSAR approaches for determining binding to albumin exist, various factors limit their ability to provide accurate binding affini...

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Détails bibliographiques
Auteurs principaux: Lexa, Katrina W., Dolghih, Elena, Jacobson, Matthew P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972100/
https://ncbi.nlm.nih.gov/pubmed/24691448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093323
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