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Tunicamycin blocks the incorporation of opsin into retinal rod outer segment membranes.

Isolated frog retinas were incubated with radiolabeled glycoprotein precursors in the presence or absence of tunicamycin (TM), a selective inhibitor of protein N-glycosylation. In dual-label incubations, TM inhibited the incorporation of [3H]mannose into total retina Cl3CCOOH-precipitable material b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fliesler, S J, Basinger, S F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3156378/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.4.1116
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