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Tunicamycin blocks the incorporation of opsin into retinal rod outer segment membranes.

Isolated frog retinas were incubated with radiolabeled glycoprotein precursors in the presence or absence of tunicamycin (TM), a selective inhibitor of protein N-glycosylation. In dual-label incubations, TM inhibited the incorporation of [3H]mannose into total retina Cl3CCOOH-precipitable material b...

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Autores principales: Fliesler, S J, Basinger, S F
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC397205/
https://ncbi.nlm.nih.gov/pubmed/3156378
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