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CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics-guided clinical trials

Individual and population differences in polymorphic cytochrome P450 enzyme function have been known for decades. The biological significance of these differences has now been deciphered with regard to drug metabolism, action and toxicity as well as disposition of endogenous substrates, including ne...

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Detalhes bibliográficos
Main Authors: Peñas-LLedó, Eva M, LLerena, Adrián
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971983/
https://ncbi.nlm.nih.gov/pubmed/24033670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12227
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