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CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics-guided clinical trials
Individual and population differences in polymorphic cytochrome P450 enzyme function have been known for decades. The biological significance of these differences has now been deciphered with regard to drug metabolism, action and toxicity as well as disposition of endogenous substrates, including ne...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971983/ https://ncbi.nlm.nih.gov/pubmed/24033670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12227 |
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