טוען...
Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving
Cue-induced cocaine craving is a major cause of relapse in abstinent addicts. In rats, cue-induced craving progressively intensifies (incubates) during withdrawal from extended-access cocaine self-administration. After ~1 month of withdrawal, incubated craving is mediated by Ca(2+)-permeable AMPARs...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971923/ https://ncbi.nlm.nih.gov/pubmed/24270186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3590 |
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