Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system

The PI 3-kinase (PI 3-K) signaling pathway is essential for Schwann cell myelination. Here we have characterized PI 3-K effectors activated during myelination by probing myelinating cultures and developing nerves with an antibody that recognizes phosphorylated substrates for this pathway. We identif...

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Detalhes bibliográficos
Main Authors: Heller, Bradley A., Ghidinelli, Monica, Voelkl, Jakob, Einheber, Steven, Smith, Ryan, Grund, Ethan, Morahan, Grant, Chandler, David, Kalaydjieva, Luba, Giancotti, Filippo, King, Rosalind H., Fejes-Toth, Aniko Naray, Fejes-Toth, Gerard, Feltri, Maria Laura, Lang, Florian, Salzer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971744/
https://ncbi.nlm.nih.gov/pubmed/24687281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307057
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