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TAp73 is essential for germ cell adhesion and maturation in testis
A core evolutionary function of the p53 family is to protect the genomic integrity of gametes. However, the role of p73 in the male germ line is unknown. Here, we reveal that TAp73 unexpectedly functions as an adhesion and maturation factor of the seminiferous epithelium orchestrating spermiogenesis...
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| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971741/ https://ncbi.nlm.nih.gov/pubmed/24662569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201306066 |
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