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Nonenzymatic sequence-specific cleavage of single-stranded DNA.

Ethylenediaminetetraacetic acid and diethylenetriaminepentaacetic acid have been attached covalently to the 5' terminus of the deoxynucleotide sequence C-A-C-A-A-T-T-C-C-A-C-A-C-A-A-C (16-mer) via an ethylenediamine linker. In the presence of Fe2+ and dithiothreitol, these reagents bring about the h...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Chu, B C, Orgel, L E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397173/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3919390/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.4.963
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