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Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1

Physical forces can activate colon cancer cell adhesion, critical for metastasis. Paxillin is phosphorylated by FAK and required for pressure-stimulated adhesion. However, whether paxillin acts as an inert scaffolding protein or whether paxillin phosphorylation is required is unknown. Transfection w...

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Bibliografische gegevens
Hoofdauteurs: Downey, C., Craig, D. H., Basson, M. D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971649/
https://ncbi.nlm.nih.gov/pubmed/18392556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-8038-x
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