Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old

OBJECTIVE: Apolipoprotein E (APOE) ε2 carriers may be protected from dementia because of reduced levels of cortical β-amyloid. In the oldest-old, however, APOE ε2 carriers have high β-amyloid plaque scores and preserved cognition. We compared different measures of β-amyloid pathology across APOE gen...

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Bibliografski detalji
Glavni autori: Berlau, Daniel J., Corrada, María M., Robinson, John L., Geser, Felix, Arnold, Steven E., Lee, Virginia M.-Y., Kawas, Claudia H., Trojanowski, John Q.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971646/
https://ncbi.nlm.nih.gov/pubmed/23474043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2012.11.011
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