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APOE ε2 is associated with intact cognition but increased Alzheimer pathology in the oldest old
Background: Many studies have examined the role of APOE genotype in the development of dementia, specifically Alzheimer disease (AD). The APOE ε4 allele (APOE4) is a risk factor for both clinical and neuropathologic AD whereas the APOE ε2 allele (APOE2) seems to be protective. This would predict, ev...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667799/ https://ncbi.nlm.nih.gov/pubmed/19255410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000343853.00346.a4 |
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