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Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis
The inhibition of triosephosphate isomerase (TPI) in glycolysis by the pyruvate kinase (PK) substrate phosphoenolpyruvate (PEP) results in a newly discovered feedback loop that counters oxidative stress in cancer and actively respiring cells. The mechanism underlying this inhibition is illuminated b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971408/ https://ncbi.nlm.nih.gov/pubmed/24598263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.130232 |
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