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Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.
Activation of cellular protein kinase C appears to be involved in the mechanism by which phorbol diesters induce differentiation of human myeloid leukemia cells (HL-60). Protein kinase C is thought to be physiologically activated by diacylglycerol derived from receptor-mediated phosphatidylinositol...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3156372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.3.815 |
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