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Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.

Activation of cellular protein kinase C appears to be involved in the mechanism by which phorbol diesters induce differentiation of human myeloid leukemia cells (HL-60). Protein kinase C is thought to be physiologically activated by diacylglycerol derived from receptor-mediated phosphatidylinositol...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Ebeling, J G, Vandenbark, G R, Kuhn, L J, Ganong, B R, Bell, R M, Niedel, J E
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1985
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397137/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3156372/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.3.815
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