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BAIT: Organizing genomes and mapping rearrangements in single cells

Strand-seq is a single-cell sequencing technique to finely map sister chromatid exchanges (SCEs) and other rearrangements. To analyze these data, we introduce BAIT, software which assigns templates and identifies and localizes SCEs. We demonstrate BAIT can refine completed reference assemblies, iden...

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Autors principals: Hills, Mark, O’Neill, Kieran, Falconer, Ester, Brinkman, Ryan, Lansdorp, Peter M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971352/
https://ncbi.nlm.nih.gov/pubmed/24028793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm486
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