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Adult and fetal human globin genes are expressed following chromosomal transfer into MEL cells.

Somatic cell hybridization of mouse erythroleukemia (MEL) cells and HEL cells, a human erythroleukemia line that produces fetal (gamma) but fails to express adult (beta) globin, was used to test whether the expression of the two human globin genes is regulated cis or trans. An experimental approach...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Papayannopoulou, T H, Lindsley, D, Kurachi, S, Lewison, K, Hemenway, T, Melis, M, Anagnou, N P, Najfeld, V
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1985
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397130/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2579380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.3.780
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