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Isolation and characterization of an RNA ligase from HeLa cells.

An RNA ligase has been purified from HeLa cells, which catalyzes the intra- and intermolecular ligation of linear RNA substrates possessing 5'-hydroxyl and 2',3'-cyclic phosphate termini in the presence of ATP or dATP. In this reaction, the 2',3'-cyclic phosphate is incorporated into a 3'-5'-phospho...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Perkins, K K, Furneaux, H, Hurwitz, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397110/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856222/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.3.684
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