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A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms

Myeloproliferative neoplasms are a varied group of disorders that can have prolonged chronic phases, but eventually accelerate and can transform into a secondary acute myeloid leukemia that is ultimately fatal. Triapine is a novel inhibitor of the M2 subunit of ribonucleotide reductase. Sequential i...

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Autors principals: Zeidner, Joshua F., Karp, Judith E., Blackford, Amanda L., Smith, B. Douglas, Gojo, Ivana, Gore, Steven D., Levis, Mark J., Carraway, Hetty E., Greer, Jacqueline M., Ivy, S. Percy, Pratz, Keith W., McDevitt, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971077/
https://ncbi.nlm.nih.gov/pubmed/24362550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.097246
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